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Br J Obstet Gynaecol. 1980 Oct;87(10):856-9.

Origin of amniocentesis-induced rises of alpha-fetoprotein concentrations in maternal serum.


An elevation of alpha-fetoprotein concentration in maternal serum occurred in 7 of 65 patients (11 per cent) following amniocentesis. Analysis of the molecular heterogeneity of the alpha-fetoprotein by chromatography on concanavalin A-agarose indicated that the source of the alpha-fetoprotein was fetal serum in three patients and amniotic fluid in four patients.

[Indexed for MEDLINE]

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