Send to

Choose Destination
J Urol. 1984 Nov;132(5):975-7.

Malacoplakia associated with vesicoureteral reflux and selective immunoglobulin A deficiency.


A case of malacoplakia involving the lower urinary tract of a young black boy, with associated bilateral vesicoureteral reflux, hydronephrosis and selective immunoglobulin A deficiency is reported. Reflux was caused by the malacoplakia. Reflux and hydronephrosis persisted despite elimination of bacterial infection and malacoplakia by drug therapy. These abnormalities were corrected by a conventional antireflux operation. Malacoplakia appears to be related to immunologic incompetence and diminished levels of intracellular cyclic 3',5' guanine monophosphate. Cholinergic agonists reverse or prevent the pathological changes of malacoplakia.

[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center