Format

Send to

Choose Destination
Lancet. 1983 Dec 17;2(8364):1379-82.

Anaerobic vaginosis (non-specific vaginitis): clinical, microbiological, and therapeutic findings.

Abstract

The effect of metronidazole on anaerobic vaginosis (non-specific vaginitis) was assessed in a double-blind, placebo-controlled study of 40 women. 19 of 20 women given metronidazole 400 mg twice a day for seven days were clinically and microbiologically cured by the time they completed treatment. All 20 women given a placebo were treatment failures, but when they were given a single 2 g dose of metronidazole, 15 showed clinical and microbiological cure a week later. 14 of the responders showed a recurrence of infection a month after treatment; this was probably due to reinfection, although persistence of infection cannot be ruled out. Findings in the clinic correlated closely with subsequent microbiological results in 133 out of 140 patient-visits, which suggests that there is no need for expensive and time-consuming laboratory investigations in this condition.

PMID:
6140492
DOI:
10.1016/s0140-6736(83)90920-0
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center