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Genetika. 1977;13(1):52-8.

[Problems of the genetics of stress. III. The differential effect of stress on the fertility of mice of differing genotypes].

[Article in Russian]

Abstract

Pre- and post-implantation embryonic mortality and the litter size in intact females and in females stressed during pregnancy were studied. These mice were the progeny of full diallele cross of 4 inbred strains (BALB/c, C3H/He, C57BL/6 and AKR/J). No genetic effects of pre-implantation losses were observed in the control group, but in the stressed group significant genetic effects (both additive and non-additive) on this character were found. Females originating from the most emotionally reactive strain (BALB/c) had a greater value of pre-implantation losses than the other animals, while the progeny of the least emotionally reactive strain (C57BL/6) had a smaller one. The litter size in the latter females was larger than in the former, in spite of the fact that the number of ovulation in RALB/c progeny was higher than that in C57BL/6 progeny. Thus, differential effect of stress on fitness was demonstrated in these experiments.

PMID:
612483
[Indexed for MEDLINE]

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