Format

Send to

Choose Destination
See comment in PubMed Commons below
Br J Anaesth. 1982 May;54(5):513-6.

Binding of tubocurarine, fazadinium, pancuronium and Org NC 45 to serum proteins in normal man and in patients with cirrhosis.

Abstract

The protein binding of four non-depolarizing neuromuscular blocking drugs-tubocurarine, fazadinium, pancuronium and Org NC45-was measured, in serum from normal patients and from patients with cirrhosis of the liver, by an ultracentrifugation method. The fraction bound to serum protein in normal patients was 56% for tubocurarine, 51% for fazadinium, 29% for pancuronium and 30% for Org NC 45. In patients with cirrhosis, the protein binding of the four drugs was similar to that obtained in the normal patient.

PMID:
6122460
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center