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Lancet. 1980 Oct 11;2(8198):793.

UNICEF/W.H.O. glucose electrolyte solution not always appropriate.



The authors defended Dr. Kahn's and Dr. Blum's suggestion, reported in the May 17, 1980 issue of Lancet, that the formula for making GES (glucose electrolyte solution), used for the management of gastroenteritis, should be determined by the age and condition of the patients in each locality. They disagreed with the proposal of Dr. Clements, reported in the July 5, 1980 issue of Lancet, that all patients could be treated with a single solution, the UNICEF/WHO CES, or with a dilution of this single solution. Recent studies confirmed that there was considerable epidemiological variation in the type and degree of electrolyte disturbances among infants with gastroenteritis. Factors such as age, nutritional status, climate, and the type of pathagens were linked to different type of electrolyte disturbances. These differences should be taken into account in formulating the appropriate GES.

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