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Cell. 1984 Dec;39(3 Pt 2):691-8.

Length determination in bacteriophage lambda tails.

Abstract

We have isolated viable mutants of bacteriophage lambda that have in-frame deletions in gene H, which codes for a minor tail protein. They produce correspondingly smaller but active gene H protein products and assemble shorter-tailed phage particles. The deficiency in tail length for each mutant corresponds to the calculated shortening of the gene H protein caused by the deletion. These results show that the H protein determines tail length and argue strongly for a scheme in which the H protein is a ruler or template that measures length during tail assembly.

PMID:
6096021
DOI:
10.1016/0092-8674(84)90476-8
[Indexed for MEDLINE]

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