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Hum Pathol. 1984 Dec;15(12):1145-6.

Kaposi's sarcoma: presence of herpes-type virus particles in a tumor specimen.

Abstract

Three Kaposi's sarcoma biopsy specimens obtained from three African patients with typical nodular cutaneous tumors were investigated morphologically for cellular modifications suggestive of a viral origin. In one case a Kaposi's sarcoma cell of the endothelial type contained a few intranuclear herpes-type viral inclusions. The present findings complement previous reports of herpes-type viral particles in Kaposi's sarcoma cultured cell lines and suggest that, at least under certain conditions, Kaposi's sarcoma cells enter a virus-producing phase.

PMID:
6094332
DOI:
10.1016/s0046-8177(84)80309-3
[Indexed for MEDLINE]

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