Format

Send to

Choose Destination
Cell. 1984 Dec;39(2 Pt 1):369-76.

P-element transformation with period locus DNA restores rhythmicity to mutant, arrhythmic Drosophila melanogaster.

Abstract

Mutations at the period (per) locus of Drosophila melanogaster disrupt several biological rhythms. Molecular cloning of DNA sequences encompassing the per+ locus has allowed germ-line transformation experiments to be carried out. Certain subsegments of the per region, transduced into the genome of arrhythmic pero flies, restore rhythmicity in circadian locomotor behavior and the male's courtship song.

PMID:
6094014
DOI:
10.1016/0092-8674(84)90015-1
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center