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Virology. 1984 Sep;137(2):428-31.

Complementation of an adenovirus 5 immediate early mutant by human cytomegalovirus.

Abstract

The initiation of the lytic cycle of adenovirus 5 requires synthesis of a transcriptional activator encoded by the viral early genetic unit, E1a. Mutant viruses lacking E1a are defective. Human cytomegalovirus activated transcription of early adenovirus genes and complemented an E1a- adenovirus mutant in cells permissive for both viruses.

PMID:
6091338
DOI:
10.1016/0042-6822(84)90236-8
[Indexed for MEDLINE]

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