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Nature. 1984 Sep 13-19;311(5982):119-23.

Occurrence of a transposition from the X-chromosome long arm to the Y-chromosome short arm during human evolution.

Abstract

DXYS1, a site showing greater than 99% DNA sequence homology between the human X and Y chromosomes, maps to the X long arm and to the Y short arm. In great apes, sequences homologous to DXYS1 are found only on the X chromosome. These findings suggest an X-Y transposition during human evolution.

PMID:
6088994
DOI:
10.1038/311119a0
[Indexed for MEDLINE]

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