Cancer-associated myasthenic (Eaton-Lambert) syndrome: distribution of abnormality and effect of treatment

J Neurol Neurosurg Psychiatry. 1984 Aug;47(8):806-12. doi: 10.1136/jnnp.47.8.806.

Abstract

Treatment with plasma exchange, steroids, immunosuppressant drugs and cytotoxic chemotherapy was effective in two cases of cancer-associated Eaton-Lambert myasthenic syndrome. The clinical improvement noted during treatment was accompanied by improvement in the electrophysiological abnormality; this was much more marked in abductor digiti minimi and trapezius than in extensor digitorum brevis.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Carcinoma, Small Cell / complications*
  • Carcinoma, Small Cell / drug therapy
  • Combined Modality Therapy
  • Electromyography
  • Humans
  • Lung Neoplasms / complications*
  • Lung Neoplasms / drug therapy
  • Male
  • Middle Aged
  • Myasthenia Gravis / diagnosis*
  • Myasthenia Gravis / therapy
  • Plasma Exchange
  • Prednisolone / therapeutic use

Substances

  • Prednisolone