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Nature. 1984 Dec 20-1985 Jan 2;312(5996):729-34.

Tissue-specific generation of two preprotachykinin mRNAs from one gene by alternative RNA splicing.

Abstract

A novel mammalian neuropeptide, the tachykinin substance K, is specified by a discrete genomic segment. Alternative RNA splicing generates two distinct mRNAs encoding the neuropeptide substance P alone or with substance K from a single preprotachykinin gene. Relative amounts of the mRNAs vary in different tissues, suggesting that the substance K-encoding sequence is regulated in a tissue-specific manner.

PMID:
6083453
[PubMed - indexed for MEDLINE]
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