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J Pharmacokinet Biopharm. 1977 Dec;5(6):625-53.

Hepatic clearance of drugs. I. Theoretical considerations of a "well-stirred" model and a "parallel tube" model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance.

PMID:
599411
[Indexed for MEDLINE]

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