Dynamic quality of HGH secretion in women with hypothalamic, maternal and simple obesity has been examined by means of the following tests: 1. glucose loading 2. hypoglycaemia following the insulin administration. Comparisons have been made with regard to normal, non-obese women. In all the obese women HGH mobilization was noted to be handicapped under the influence of the after-insulin hypoglycaemia. In some patients of all the obesity groups a paradoxical response of HGH secretion after the glucose administration was noted. In some cases of the hypothalamic and simple obesity groups there occurred a paradoxical response of HGH secretion relating to the insulin hypotlycaemia test. Differences discovered in the dynamics of HGH secretion with appropriateness to the etiopathogenetic forms of obesity are slight: their significance is rather quantitative than qualitative.