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Biochem J. 1965 Sep;96(3):588-94.

Characteristics of arginases from ureotelic and non-ureotelic animals.

Abstract

1. Livers of ureotelic and uricotelic animals possess the capacity, to a varying extent, of hydrolysing l-arginine and other guanidino compounds. 2. Three different enzymes responsible for such activity have been separated and partially characterized. They are the ;ureotelic' arginase, the ;uricotelic' arginase (both of them specific for l-arginine) and the guanidinobutyrate ureohydrolase (able to hydrolyse beta-guanidinopropionate, gamma-guanidinobutyrate and d-arginine but not l-arginine or guanidinoacetate). 3. The implication of the advent of a ;ureotelic' arginase in the integration of the Krebs-Henseleit cycle is discussed.

PMID:
5862400
PMCID:
PMC1207192
DOI:
10.1042/bj0960588
[Indexed for MEDLINE]
Free PMC Article

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