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Arzneimittelforschung. 1979;29(10):1640-2.

[Chromatographic separation of racemic thalidomide and teratogenic activity of its enantiomers (author's transl)].

[Article in German]

Abstract

Racemic thalidomide is chromatographically separated on optically active polyamide giving both enantiomers. After i.p. administration only the S-(-)-enantiomer is teratogenic on SWS mice and Natal rats.

PMID:
583234
[Indexed for MEDLINE]

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