Send to

Choose Destination
J Embryol Exp Morphol. 1979 Aug;52:105-13.

Evidence for a positional memory in the development of the chick wing bud.


Grafts of quail zones of polarizing activity (ZPA), treated with 10000 rad gamma-radiation, tend to remain at the base of a limb. Their signalling ability is not passed on to more distal tissue, but the limb goes on to produce a reduplication. This suggests that the effect of a ZPA can be remembered in its absence, and explains why a normal limb can develop if its ZPA is removed.

[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for HighWire
Loading ...
Support Center