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Biochim Biophys Acta. 1979 Dec 14;581(2):365-70.

Interaction of alpha-actinin, filamin and tropomyosin with F-actin.


The abilities of alpha-actinin, filamin and tropomyosin to bind F-actin were examined by cosedimentation experiments. Results indicated that smooth muscle alpha-actinin and filamin can bind to actin filaments simultaneously with little evidence of competition. In contrast, tropomyosin exhibits marked competition with either filamin or alpha-actinin for sites on actin filaments.

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