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Science. 1971 Dec 24;174(4016):1354-6.

Stage 4 sleep: influence of time course variables.

Abstract

Age, length of prior wakefulness, length of time asleep, and a circadian influence all affect stage 4 sleep. The amount of stage 4 sleep decreases as subject's age increases and as time asleep increases. Longer periods of wakefulness before sleep result in greater amounts of stage 4 sleep in the first 3 hours of sleep. Sleep periods that begin at times other than the regular onset time tend to produce less stage 4 sleep; this decrease suggests a circadian effect.

PMID:
5135723
DOI:
10.1126/science.174.4016.1354
[Indexed for MEDLINE]

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