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Br J Cancer. 1971 Jun;25(2):270-5.

A new anti-oestrogenic agent in late breast cancer. An early clinical appraisal of ICI46474.

Abstract

An introductory clinical trial of the anti-oestrogenic agent IC146474 in late or recurrent carcinoma of the breast is described.Forty-six patients have been treated, of whom 10 have shown a good response. This is of the same order as that seen with oestrogens and androgens.The particular advantage of this drug is the low incidence of troublesome side effects.

PMID:
5115829
PMCID:
PMC2008453
DOI:
10.1038/bjc.1971.33
[Indexed for MEDLINE]
Free PMC Article

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