Abstract
Urinary metabolites before dental treatment were compared in a group of patients with dental phobia and in a matched control group. Plasma adrenaline, noradrenaline, and free fatty acids were estimated before treatment, immediately after sedation with diazapam 0.2 mg/kg body weight in the phobic patients, during induction of oral anaesthesia, and during and after surgery. Patients with dental phobia had significantly higher levels of adrenaline, which were only temporarily lowered by sedation, and which during treatment remained consistently higher than those of control patients.
MeSH terms
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Adolescent
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Adult
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Anesthesia, Dental
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Anesthesia, Local
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Anxiety / blood*
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Anxiety / urine
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Catecholamines / blood*
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Catecholamines / urine
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Chromatography, Paper
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Dentistry, Operative*
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Diazepam / therapeutic use
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Epinephrine / blood
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Fatty Acids, Nonesterified / blood
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Fluorometry
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Heart Rate
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Humans
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Middle Aged
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Norepinephrine / blood
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Phobic Disorders / blood
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Phobic Disorders / drug therapy
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Phobic Disorders / physiopathology
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Phobic Disorders / urine
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Vanilmandelic Acid / urine
Substances
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Catecholamines
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Fatty Acids, Nonesterified
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Vanilmandelic Acid
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Diazepam
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Norepinephrine
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Epinephrine