Mutant of Bacillus subtilis demonstrating the requirement of lysis for growth

J Bacteriol. 1971 Feb;105(2):629-36. doi: 10.1128/jb.105.2.629-636.1971.

Abstract

A temperature-sensitive mutant of Bacillus subtilis which has impaired ability to autolyze was isolated. The growth rate of mutant cells at high temperature can be increased by the addition of egg-white lysozyme or a B. subtilis autolysin. Experiments with this mutant show that lysis is essential for cell growth.

MeSH terms

  • Bacillus subtilis / cytology
  • Bacillus subtilis / drug effects
  • Bacillus subtilis / growth & development*
  • Bacillus subtilis / isolation & purification
  • Bacteriolysis*
  • Cell Wall / drug effects
  • Chlorides
  • Culture Media

Substances

  • Chlorides
  • Culture Media