Format

Send to

Choose Destination
Science. 1968 Jul 26;161(3839):370-1.

Differentiated rat glial cell strain in tissue culture.

Abstract

Rat glial tumors, induced by injections of N-nitrosomethylurea, were plated and propagated in culture. Among a few cell strains obtained, one clone contains S-100 protein, which is unique to brain in vertebrates. Stationary-phase cultures contain approximately ten times more S-100 protein per cell than exponentially growing cells. When injected into newborn rats, cells producing S-100 grew as a glial tumor, which contained S-100 protein.

PMID:
4873531
DOI:
10.1126/science.161.3839.370
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for HighWire
Loading ...
Support Center