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Science. 1974 Feb 1;183(4123):416-7.

Fecal bacterial beta-glucuronidase: control by diet.

Abstract

The effect of a mixed Western, high meat diet or a nonmeat diet on the intestinal bacterial beta-glucuronidase activity was studied in human volunteers. This enzyme was significantly higher in stools of subjects on a high meat diet as compared to the nonmeat regimen. Thus, intestinal flora of subjects on a high meat diet was more able to hydrolyze glucuronide conjugates than that of individuals on a nonmeat diet. This, in turn, may raise the amount of substances, such as carcinogens, within the colonic lumen.

PMID:
4808971
DOI:
10.1126/science.183.4123.416
[Indexed for MEDLINE]

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