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J Neurol Neurosurg Psychiatry. 1973 Oct;36(5):753-6.

Biochemical aspects of motor neurone disease--Madras pattern.

Abstract

A detailed study of four cases of MND-Madras has shown a significantly low plasma citrate level in these subjects. Comparison with other related groups of neurological disorders indicates the citrate/pyruvate ratio to be of diagnostic value in MND-Madras. This seems to suggest that the pathophysiology of MND-Madras may centre round altered citrate metabolism.

PMID:
4753872
PMCID:
PMC494453
[Indexed for MEDLINE]
Free PMC Article
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