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Science. 1973 Feb 16;179(4074):702-4.

Cholesterol: vitamin C controls its transformation to bile acids.

Abstract

Cholesterol accumulates in the blood serum and in the liver of guinea pigs with chronic latent vitamin C deficiency. The reason for this is the decreased rate of transformation of cholesterol to bile acids in the liver of animals deficient in vitamin C. A significant direct correlation exists between the vitamin C concentration in the liver and the rate of cholesterol transformation to bile acids.

PMID:
4685043
DOI:
10.1126/science.179.4074.702
[Indexed for MEDLINE]

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