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Proc Natl Acad Sci U S A. 1972 Jun;69(6):1583-6.

Circadian rhythms in drinking behavior and locomotor activity of rats are eliminated by hypothalamic lesions.

Abstract

Bilateral electrolytic lesions in the suprachiasmatic nuclei permanently eliminated nocturnal and circadian rhythms in drinking behavior and locomotor activity of albino rats. The generation of 24-hr behavioral rhythms and the entrainment of these rhythms to the light-dark cycle of environmental illumination may be coordinated by neurons in the suprachiasmatic region of the rat brain. Destruction of the medial preoptic area had no effect on 24-hr drinking rhythms.

PMID:
4556464
PMCID:
PMC426753
DOI:
10.1073/pnas.69.6.1583
[Indexed for MEDLINE]
Free PMC Article

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