1,6-Di-O-methanesulphonyl-2,3-4,5-dianhydro-L-iditol, a new potential antitumour agent. Biological investigations

Arzneimittelforschung. 1973 Jul;23(7):961-7.
No abstract available

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use*
  • Blood Cells / drug effects
  • Bone Marrow / drug effects
  • Bone Marrow Cells
  • DNA / biosynthesis
  • DNA, Neoplasm / biosynthesis
  • Dogs
  • Drug Evaluation, Preclinical
  • Ethers, Cyclic / metabolism
  • Ethers, Cyclic / pharmacology
  • Ethers, Cyclic / toxicity
  • Lethal Dose 50
  • Mannitol / pharmacology
  • Mesylates / metabolism
  • Mesylates / pharmacology*
  • Mesylates / toxicity
  • Mice
  • Mitosis / drug effects
  • Neoplasm Metastasis
  • Neoplasm Transplantation
  • Neoplasms, Experimental / drug therapy*
  • Neoplasms, Experimental / metabolism
  • RNA / biosynthesis
  • RNA, Neoplasm / biosynthesis
  • Rats
  • Sugar Alcohols / metabolism
  • Sugar Alcohols / pharmacology*
  • Sugar Alcohols / toxicity

Substances

  • Antineoplastic Agents
  • DNA, Neoplasm
  • Ethers, Cyclic
  • Mesylates
  • RNA, Neoplasm
  • Sugar Alcohols
  • Mannitol
  • RNA
  • DNA