Format

Send to

Choose Destination
See comment in PubMed Commons below
Science. 1969 Sep 19;165(3899):1264-6.

Diphosphonates inhibit formation of calcium phosphate crystals in vitro and pathological calcification in vivo.

Abstract

Two diphosphonates containing the P-C-P bond, CH(3)C(OH)(PO(3)HNa)(2) and H(2)C(PO(3)HNa)(2), inhibit the crystallization of calcium phosphate in vitro and prevent aortic calcification of rats given large amounts of vitamin D(3). The diphosphonates therefore have effects similar to those described for compounds containing the P-O-P bond but are active when administered orally.

PMID:
4308521
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Support Center