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Biochem J. 1979 Aug 15;182(2):625-8.

Comparison of superoxide with other reducing agents in the biological production of hydroxyl radicals.

Abstract

Iron--EDTA was shown to catalyse OH. production from H2O2 and ascorbate by a mechanism largely independent of superoxide. When ascorbate and superoxide were both present, the ascorbate mechanism was more important than superoxide as a source of OH., and would appear to be more significantly biologically.

PMID:
41521
PMCID:
PMC1161347
DOI:
10.1042/bj1820625
[Indexed for MEDLINE]
Free PMC Article

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