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J Mol Biol. 1985 Dec 20;186(4):791-803.

Covalent structure of three phase-1 flagellar filament proteins of Salmonella.

Abstract

Using recombinant DNA techniques, the covalent structure was determined for three flagellar filament proteins produced by Salmonella serotypes with phase-1 antigens a, c and d. Comparison of the results obtained, together with previous results for antigen i, indicated an overall structure in which conservation of amino acid sequence was absolute at both ends of the molecule and proceeded inwards with progressively greater variation. Very few differences in nucleotide sequence were detected in regions of amino acid conservation, which suggested that these areas of the gene may be involved in regulatory functions.

PMID:
4093985
DOI:
10.1016/0022-2836(85)90397-3
[Indexed for MEDLINE]

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