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Vopr Pitan. 1985 Jul-Aug;(4):51-4.

[Adrenal cortex functional activity in pantothenate deficiency and the administration of the vitamin or its derivatives].

[Article in Russian]

Abstract

Study of the corticosteroid content in the adrenals and blood of rats under pantothenate deficiency has demonstrated a decrease in adrenocortical function. A single administration of pantothenate in a dose of 3.3 mg/kg reduced the influence of hypovitaminosis on the adrenals. The pantothenate derivatives (pantethine, 4'-phosphopantothenate and CoA in particular) injected to intact animals in a single dose equimolar to 3.3 mg/kg calcium pantothenate per kg bw had a marked steroidogenous effect.

PMID:
4060684
[Indexed for MEDLINE]

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