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Gerontology. 1985;31(5):315-20.

Glucose phosphate isomerase activity in C57BL/6 and a mice of different ages.


Glucose phosphate isomerase (GPI) enzyme activity was measured in two strains of mice, A/HeNNial (Gpi-1a) and C57BL/6NNia1 (Gpi-1b). Seven solid tissues (muscle, brain, heart, kidney, liver, lung, spleen) and three cell types (peripheral blood lymphocytes, spleen lymphocytes, erythrocytes) were analyzed for GPI activity in mice from 6 to 36 months of age. No major changes in enzyme activity with age were found. The most striking observation was that A/HeNNial mice showed a significantly higher GPI activity than C57BL/6NNia1 mice in four of the solid tissues (muscle, heart, kidney, spleen) and two of the cell types (peripheral blood lymphocytes, erythrocytes) analyzed.

[Indexed for MEDLINE]

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