Immunological sensitization following inapparent infection with dengue virus type 3 in rhesus monkeys

Experientia. 1977 Mar 15;33(3):330-1. doi: 10.1007/BF02002810.

Abstract

Rhesus monkeys previously given dengue virus type 3, without apparent viremia or antibody response, exhibited a secondary-type response upon reinoculation. These data suggest that monkeys can be immunologically sensitized to dengue virus without detectable antibody production.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Dengue Virus / drug effects
  • Dengue Virus / immunology*
  • Female
  • Haplorhini
  • Immunization*
  • Macaca / immunology*
  • Macaca mulatta / immunology*
  • Methylnitronitrosoguanidine / pharmacology
  • Virus Replication / drug effects

Substances

  • Methylnitronitrosoguanidine