Abstract
Rhesus monkeys previously given dengue virus type 3, without apparent viremia or antibody response, exhibited a secondary-type response upon reinoculation. These data suggest that monkeys can be immunologically sensitized to dengue virus without detectable antibody production.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Dengue Virus / drug effects
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Dengue Virus / immunology*
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Female
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Haplorhini
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Immunization*
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Macaca / immunology*
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Macaca mulatta / immunology*
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Methylnitronitrosoguanidine / pharmacology
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Virus Replication / drug effects
Substances
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Methylnitronitrosoguanidine