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Biometrics. 1985 Mar;41(1):153-65.

Maximum likelihood estimation of variance components for a multivariate mixed model with equal design matrices.


An algorithm is described for estimating variance and covariance components by restricted maximum likelihood for a multivariate mixed two-way classification with equal design matrices. The procedure involves a transformation to canonical scale, effectively reducing a q-variate analysis to q corresponding univariate analyses. A small numerical example is given as well as a large-scale practical application.

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