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J Gen Microbiol. 1985 Apr;131(4):913-7.

Is phase variation in Bordetella caused by mutation and selection?

Abstract

In vitro growth conditions of Bordetella bronchiseptica led to an enrichment of phase variants. The frequency of phase variation was about 10(-6) per cell per generation. Therefore phase variation in Bordetella may result from a random mutation in a controlling region, followed by selection.

PMID:
3989513
DOI:
10.1099/00221287-131-4-913
[Indexed for MEDLINE]
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