[Renewal of hematopoietic stem cell clones in long-term bone marrow cultures]

Biull Eksp Biol Med. 1985 Mar;99(3):346-8.
[Article in Russian]

Abstract

In long-term cultures of murine bone marrow, clonal succession of hemopoietic cells was observed as measured by karyologic analysis. There were high oscillations in self-renewal of CFUs in the cultures. A close correlation between the CFUmix karyotype and mitotic non-adherent cells in culture (but not between these cell types and CFUs) was revealed.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Female
  • Hematopoietic Stem Cells / cytology*
  • In Vitro Techniques
  • Karyotyping
  • Male
  • Mice
  • Mice, Inbred CBA
  • Time Factors