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Diabetologia. 1985 Feb;28(2):76-9.

Glycosylated haemoglobin in normal pregnancy: a longitudinal study with two independent methods.

Abstract

Twenty-one women completed a longitudinal study of glycosylated haemoglobin in normal pregnancy. Glycosylated haemoglobin levels were measured using two independent techniques (ion-exchange column and colorimetric). Concurrent serial oral glucose tolerance tests (75-g glucose load) and erythrocyte indices were obtained. Changes in mean glycosylated haemoglobin were similar with both techniques with a nadir at 17 weeks, a peak at delivery (p less than 0.002 versus 17 weeks) and a fall post-partum. Glycosylated haemoglobin levels in abnormal pregnancies, e.g. diabetic, should be interpreted in the knowledge of these physiological changes.

PMID:
3979692
DOI:
10.1007/bf00279919
[Indexed for MEDLINE]

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