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Am J Clin Nutr. 1985 Mar;41(3):540-4.

Anthropometric and calorimetric evidence for the protein sparing effects of a new protein supplemented low calorie preparation.


A commercial protein sparing modified fast (PSMF) preparation has been evaluated for the protein sparing effects in 15 morbidly obese patients. During a 500 kcal preparation, given during a 6-week period, mean body weight and BMI decreased significantly. Total body fat decreased from 55.8 to 41.4 kg and lean body mass and arm muscle circumference (AMC) remained unchanged. Using indirect calorimetry and under the same degree of energy expenditure, carbohydrate metabolic consumption was significantly diminished (166 to 61 g/24 hr; p less than 0.001) but fat consumption was increased (116 to 155 g/24 hr; p less than 0.05) while the metabolic turn-over of protein was unchanged. This new presented PSMF preparation seems to present the typical properties of a protein sparing modified fast.

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