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Biochem Pharmacol. 1986 Jan 15;35(2):231-5.

Subcellular localization of epoxide hydrolase in mouse liver and kidney.


The subcellular distribution of epoxide hydrolase activity towards TSO and HEOM in mouse liver and kidney was investigated using zonal rotor centrifugation. Epoxide hydrolase activity towards TSO was found predominantly in the soluble fraction with peroxisomes accounting for activity in the particulate fractions. Renal particulate activity towards HEOM was found predominantly in the microsomes.

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