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Nature. 1986 Jan 23-29;319(6051):291-5.

A gradient of sex linkage in the pseudoautosomal region of the human sex chromosomes.

Abstract

Three independent pseudoautosomal loci are linked to sex determination at frequencies which define a gradient of linkage. The segregation patterns of these loci indicate that X/Y recombination results from a single obligatory meiotic crossing-over in the pseudoautosomal region. Recombination in male germ cells in the terminal regions of the short arms of the X and Y chromosomes in 10-fold greater than between the same regions of the X chromosomes in female germ cells.

PMID:
3941746
DOI:
10.1038/319291a0
[Indexed for MEDLINE]

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