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Infection. 1985 May-Jun;13(3):134-6.

An amphotericin B-resistant case of rhinocerebral mucor mycosis.

Abstract

A 51-year-old male patient with diabetes mellitus complicated by ketoacidotic imbalance developed a rhinocerebral mucor mycosis that advanced despite early amphotericin B therapy and extensive surgical intervention. The MIC of amphotericin B for the isolated mucor species was 64 mg/l, meaning that in vitro resistance also existed. Only long-term treatment with ketoconazole (600 mg/day, perorally) was successful in curing the disease.

PMID:
3928496
DOI:
10.1007/bf01642873
[Indexed for MEDLINE]

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