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Am J Vet Res. 1985 Feb;46(2):332-5.

Inhibition of phagosome-lysosome fusion in macrophages by soluble extracts of virulent Brucella abortus.


Water extracts of virulent Brucella abortus were able to inhibit phagosome-lysosome fusion in unelicited murine peritoneal macrophages following ingestion of yeast. Extracts from an avirulent strain were unable to produce a similar effect. Lipopolysaccharide from B abortus did not appear to be involved with the ability of the extracts to inhibit fusion.

[Indexed for MEDLINE]

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