Format

Send to

Choose Destination
J Clin Psychiatry. 1985 Feb;46(2 Pt 2):4-8.

Trimipramine in physical illness with depression.

Abstract

To assess whether tricyclic antidepressants are useful in patients with a serious physical disorder who develop symptoms of major depression, 42 medically ill outpatients who met RDC criteria for endogenous major depression and had a Raskin depression score of at least 7 were studied. The patients were randomly assigned to a 6-week trial of trimipramine or placebo under double-blind conditions. In the placebo group, depressive symptoms improved when the physical disorder improved; in the trimipramine group, improvement was seen in the depressive symptoms even when there was no concomitant improvement in physical condition.

PMID:
3881418
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center