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FEBS Lett. 1985 Oct 21;191(1):39-44.

Sequence of the OXA2 beta-lactamase: comparison with other penicillin-reactive enzymes.

Abstract

The nucleotide sequence of the unusual plasmid-mediated OXA2 beta-lactamase is presented, and compared with other beta-lactamases. The OXA2 enzyme has similar features at the presumed active site, but no other significant regions of homology with other penicillin-reactive enzymes. The active site homology may therefore represent convergent evolution of otherwise dissimilar genes.

PMID:
3876949
DOI:
10.1016/0014-5793(85)80989-3
[Indexed for MEDLINE]
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