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Chronobiol Int. 1985;2(4):277-80.

A hypernychthemeral sleep-wake syndrome: a treatment attempt.

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Sleep Laboratory, Faculty of Medicine, Technion--Isreal Institute of Technology, Haifa.


The wake and sleep-onset times of a patient with a sleep-wake cycle longer than 24 hr were recorded by the patient for 4 years. During this time, the patient found himself unable to maintain a 24-hr sleep-wake schedule. When treated with 1-2 mg clonazepam, taken nightly, he was able to become entrained to a 24-hr day. Despite entrainment of his sleep-wake cycle, the patient reported depression, lack of motivation and fatigue and chose not to continue taking the drug.

[Indexed for MEDLINE]

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