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Clin Chest Med. 1985 Dec;6(4):563-75.

Control of ventilation during sleep.


Ventilatory responses to chemostimulation are reduced during NREM sleep and fall further during REM sleep. These reductions are probably due to a combination of decreased basal metabolic rate during sleep, altered neuromuscular function, and increased cerebral blood flow. The decreased responses are important in the production of hypoxemia during sleep in patients with hypoxic lung disease.

[Indexed for MEDLINE]

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