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Nature. 1979 Jun 28;279(5716):778-81.

Cloned fragments of the plasmid ColV,I-K94 specifying virulence and serum resistance.

Abstract

A cloned BamH1-generated fragment of ColV,I-K94 increased the virulence of Escherichia coli, causing an approximately 100-fold reduction in LD50 for chicks. A genetic determinant for resistance to the bactericidal effects of serum was mapped to a 5,300 base-pair sequence within the fragment. Neither colicin V nor immunity to colicin V affected the pathogenicity of E. coli for chicks.

PMID:
377103
DOI:
10.1038/279778a0
[Indexed for MEDLINE]

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