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Am J Med. 1986 Oct;81(4):727-33.

Giant cell arteritis of the legs. Clinical isolation of severe disease with gangrene and amputations.

Abstract

Giant cell arteritis rarely presents as clinically advanced extra-ocular ischemia or gangrene. Clinically isolated leg involvement with amputation is even more unusual. A 69-year-old woman is described who had giant cell arteritis necessitating bilateral leg amputations. No other clinical sequelae have ensued during a four-year follow-up period. Temporal artery biopsy subsequent to the amputations revealed no arteritis. Disparities between the usual patterns of clinical and anatomic involvement in giant cell arteritis underlie the potential diagnostic difficulties in this disease. Although typically diagnostic, temporal artery biopsy does not always bridge the clinical and anatomic disparities.

PMID:
3766604
DOI:
10.1016/0002-9343(86)90568-1
[Indexed for MEDLINE]

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